In vitro receptor binding studies have demonstrated no detectable affinity of cetirizine for histamine receptors other than the H1 receptors.
Children aged 1-2 years: 2.
They can add to sleepiness caused by cetirizine.
Because animal studies are not always predictive of human response, cetirizine should be used in pregnancy only if clearly needed.
Children from 6 to 12 months : 2.
Correction of the dose is necessary only if the patient with liver failure also has concomitant renal failure.